The World Health Organization (WHO) recommends artemisinin-based combination therapy (ACT) for the treatment of uncomplicated malaria due to Plasmodium falciparum (P. falciparum). ACTs recommended by WHO combine an artemisinin derivative such as artemether, artesunate or dihydroartemisinin with an effective antimalarial medicine. The five currently recommended ACTs are listed in the WHO guidelines for the treatment of malaria, 2010 (1).
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